Fluidic system for high throughput preparation of polymeric microparticles and nanoparticles

Description:

This technology encompasses a fiber fluidic system designed for the production of particles, utilizing a cylinder packed with elongated fibers. The system operates by introducing a constrained phase fluid and a free phase fluid through separate openings at one end of the cylinder. These fluids interact along the lengths of the fibers to form particles, which are then collected from the opposite end of the cylinder. The process is capable of producing particles with sizes ranging from 1 nm to 100 μm, with specific embodiments achieving monodispersed particles between 5 nm and 2.5 μm. The fibers can be either hydrophilic or hydrophobic, and the system allows for continuous particle production by maintaining a steady flow of the fluids.

Key Advantages:

• Precise control over particle size, ranging from 1 nm to 100 μm.
• Capability to produce monodispersed particles, enhancing product uniformity.
• Versatility in particle production through the use of hydrophilic or hydrophobic fibers.
• Continuous production process for efficient particle manufacturing.
• Compatibility with a wide range of fluids, including aqueous and precursor solutions.

Problems Solved:

• Inconsistent particle sizes in traditional manufacturing methods.
• Limited control over particle dispersion in current technologies.
• Inefficiencies in batch production of particles.
• Challenges in producing particles with specific chemical or physical properties.

Market Applications:

• Drug delivery systems for targeted therapy.
• Advanced materials for electronics and photonics.
• Cosmetics, including uniform polymer beads for creams and lotions.
• Industrial coatings and paints requiring precise particle sizes.
• Catalysts and enzymes for chemical processing.