NETFIO-MS(Network-Based Functional Imaging Output for Evaluating Multiple Sclerosis)

Description:

NETFIO-MS is an innovative medical image analysis tool designed for use with resting-state functional MRI (rsfMRI) to quantitatively assess functional network-based disease burden in MS patients. By focusing on the functional network properties related to neurodegeneration, NETFIO-MS offers a novel approach to the early and accurate diagnosis of MS, as well as the monitoring of disease progression. This tool is based on the functional MACM (fMACM) model, which identifies localized neurodegeneration in MS, marking a significant advancement over traditional methods that primarily focus on demyelinating lesions.

Key Advantages:

• Provides a quantitative, per-patient analysis of MS disease burden.
• Enables early and accurate MS diagnosis by focusing on functional network changes rather than just structural abnormalities.
• Improves monitoring of disease progression through sensitive detection of functional abnormalities.
• Offers a new perspective on MS pathophysiology by highlighting the importance of grey matter atrophy and its correlation with cognitive impairment and clinical disability.

Problems Solved:

• Reduces misdiagnosis of MS and its associated clinical and economic consequences.
• Overcomes the limitations of qualitative evaluation and group-wise testing in detecting subtle grey matter changes.
• Addresses the need for better correlation between MRI findings and disease progression.

Market Applications:

• Clinical diagnostics for early and accurate detection of Multiple Sclerosis.
• Monitoring of disease progression in MS patients.
• Research tool in neurology for studying MS pathophysiology and treatment effectiveness.