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Use of Nanoclays for the Removal of Non-Plasmid DNA Components from Cellular Extracts

Description: This technology introduces a groundbreaking method for purifying pDNA through the use of nanoclay particles. By adding these specially formulated nanoclays to a mixture of biomolecular materials, such as cellular extracts, key contaminants and extraneous materials can be selectively bound and removed. This process represents a significant...

Published: 4/14/2025 | Inventor(s): Lysle Lewis, Drew Sowersby

Keywords(s): Nanoclays, Non-Plasmid DNA

Category(s): Nanotechnology, Life Science, Chemistry

Ecofriendly Skin Safe Absorbent

Description: This technology involves the extraction of guar gum (GG) from the Cyamopsis tetragonalobus plant and its combination with alginic acid to create a biodegradable superabsorbent polymer. Guar gum, a safe and eco-friendly polymer, is cultivated primarily in India and is known for its solubility and biodegradability. By crosslinking it with...

Published: 4/14/2025 | Inventor(s): Sujata Mandal, Sangchul Hwang

Keywords(s): Ecofriendly, Skin Safe Absorbent

Category(s): Materials, Life Science, Energy/Environment

Novel truncated miRNA-506-3p analogs for Neuroblastoma differentiation therapy

Description: Our research has developed a series of shortened miR-506-3p analogs designed to maintain strong differentiation-inducing activities comparable to the wildtype miR-506-3p. These analogs have been tested for their ability to induce neurite outgrowth and cell growth arrest in neuroblastoma cells, demonstrating significant potential for therapeutic...

Published: 4/14/2025 | Inventor(s): Liqin Du, Nakya Mesa-Diaz, Mitchell Smith

Keywords(s): Childhood Cancer, Differentiation Therapy, Differentiation-Inducing Agent, MicroRNA, miR-506-3p, Neuroblastoma, Shortened miRNA, Truncated Analog, Wildtype (WT)

Category(s): Life Science, Cancer

Modulating stress responses by a novel chromatin-associated guide RNA derived from tRNA

Description: This technology revolves around the discovery of CANG-RNA, a type of tRNA-derived RNA fragment, and its critical role in plant immunity. By interacting with the genome, CANG-RNA facilitates a rapid and extensive transcriptional reprogramming, enabling plants to mount a strong defense against pathogens such as Pseudomonas syringae pv. tomato....

Published: 4/14/2025 | Inventor(s): Hong-Gu Kang, Sung-Il Kim

Keywords(s): Bio-Active RNA, Immunization, Stress, Transcriptional Reprogramming

Category(s): Agriculture, Life Science

NETFIO-MS(Network-Based Functional Imaging Output for Evaluating Multiple Sclerosis)

Description: NETFIO-MS is an innovative medical image analysis tool designed for use with resting-state functional MRI (rsfMRI) to quantitatively assess functional network-based disease burden in MS patients. By focusing on the functional network properties related to neurodegeneration, NETFIO-MS offers a novel approach to the early and accurate diagnosis...

Published: 4/14/2025 | Inventor(s): Larry Price

Keywords(s): Atrophy-Based Functional Network, Expanded Disability, Network Degeneration Hypothesis

Category(s): Life Science, Software, Data/AI

Herbicide and Environmental Stress Resistant Plants and Seeds

Description: This technology encompasses the development and use of genetically modified plants or seeds that are resistant to specific herbicides and various environmental stresses. By incorporating mutated genes, such as pic30 or its homologs, these plants or seeds can withstand conditions such as drought, plant diseases, and both biotic and abiotic...

Published: 4/14/2025 | Inventor(s): Nihal Dharmasiri, Sunethra Dharmasiri, Praveen Kathare

Keywords(s):

Category(s): Agriculture, Life Science

Photoactivatable Cancer Prodrug Photoactivatable Ruthenium Compounds for Cancer Treatment

Description: This technology introduces a new class of photoactivatable compounds based on ruthenium for the treatment of cancer. Leveraging the principles of photodynamic therapy (PDT), these compounds are designed to be activated by light to target and disrupt cancer cells selectively, while sparing healthy tissues. This innovative approach aims...

Published: 4/14/2025 | Inventor(s): Alexander Kornienko, Tania Betancourt, Shuster Bonnet, Vincent van Rixel

Keywords(s): Cancer Treatment, Photoactivatable Ruthenium Compounds, Photodynamic Therapy Photodynamic Therapy

Category(s): Cancer, Chemistry, Life Science

Health Assessment via Eye Movement Biometrics

Description: This technology encompasses various methods and systems for assessing brain injuries and conditions like autism and fatigue by measuring and analyzing eye movements. By determining specific values from the eye movement data, such as feature vectors or behavioral scores, the system can assess whether an individual has suffered from brain...

Published: 4/14/2025 | Inventor(s): Oleg Komogortsev

Keywords(s): Autism, Brain Injury, Eye Movement, Fatigue

Category(s): Software, Life Science