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PdOpDH and Copper-Responsive Pathway in Pseudogymnoascus destructans

Description: The technology investigates the role of the enzyme Opine Dehydrogenase (PdOpDH) in the production of copper-binding metabolites (opine metallophores) by the fungus Pseudogymnoascus destructans, the causative agent of White Nose Syndrome in bats. This enzyme, along with the copper-responsive pathway, enables the fungus to acquire essential...

Published: 5/27/2026 | Updated: 5/27/2026 | Inventor(s): Ryan Peterson

Keywords(s): Chemistry, Fungal Pathogen Metallophore Biosynthesis, Metal Stress Adaption, Pharmaceutical Chemistry, Pharmaceuticals

Category(s): Life Science, Chemistry, Pharmaceuticals

Novel Antifungal Agents

Description: This technology encompasses the design and synthesis of over two dozen unique heterocyclic compounds that demonstrate antifungal efficacy against a variety of plant pathogens. These compounds are structurally distinct from existing antifungal agents, suggesting novel mechanisms of action that may overcome resistance issues. The innovation...

Published: 3/10/2026 | Updated: 3/10/2026 | Inventor(s): Sean Kerwin

Keywords(s): Agricultural Technology, Antifungal Research, Pharmaceuticals

Category(s): Pharmaceuticals, Agriculture