Search Results - life+science

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Log-Regulated Laplacian Sparse Functional Connectivity of fMRI Data

Description: This technology introduces two novel functional connectivity (FC) estimation methods—a Log-Regularized Laplacian Graph estimator and a K-Nearest Neighbors (KNN) Graph estimator—that generate sparse FC matrices from resting-state fMRI BOLD time series. By pruning weak and irrelevant connections, these methods reduce noise and...

Published: 12/16/2025 | Inventor(s): Mylène Queiroz de Farias, Juliana Danso

Keywords(s): Data, Machine Learning, Neuroimaging

Category(s): Data/AI, Life Science

Novel Anti-MRSA Medicinal Compound with Azo-Functionalized Heterocyclic Structure

Description: This invention introduces a novel medicinal compound based on a heterocyclic system containing azo functionality, synthesized via azo-coupling with 4-amino-benzimidazole. It demonstrates significant efficacy against methicillin-resistant Staphylococcus aureus (MRSA) with a minimum inhibitory concentration of 12 µM, coupled with a...

Published: 11/24/2025 | Inventor(s): Alexander Kornienko, Puppala Sathish, Carson King, Riaz Hossain

Keywords(s): Antibacterial Drug Development, Pharmaceuticals

Category(s): Chemistry, Life Science

SafeSpace Pro

Description: SafeSpace Pro combines key design principles such as wayfinding, memory aids, lighting, and flooring assessments into a single platform to evaluate and improve environments for independent living, especially for individuals with dementia or Alzheimer’s. By providing actionable feedback and AI-powered recommendations, it helps mitigate...

Published: 11/24/2025 | Inventor(s): Mohamad Adi, Mais Aljunaidy

Keywords(s): Dementia Care Technology, Healthcare, Healthcare Technology

Category(s): Data/AI, Software, Life Science

Use of Nanoclays for the Removal of Non-Plasmid DNA Components from Cellular Extracts

Description: This technology introduces a groundbreaking method for purifying pDNA through the use of nanoclay particles. By adding these specially formulated nanoclays to a mixture of biomolecular materials, such as cellular extracts, key contaminants and extraneous materials can be selectively bound and removed. This process represents a significant...

Published: 11/11/2025 | Inventor(s): Lysle Lewis, Drew Sowersby

Keywords(s): Nanoclays, Non-Plasmid DNA

Category(s): Nanotechnology, Life Science, Chemistry

Ecofriendly Skin Safe Absorbent

Description: This technology involves the extraction of guar gum (GG) from the Cyamopsis tetragonalobus plant and its combination with alginic acid to create a biodegradable superabsorbent polymer. Guar gum, a safe and eco-friendly polymer, is cultivated primarily in India and is known for its solubility and biodegradability. By crosslinking it with...

Published: 11/11/2025 | Inventor(s): Sujata Mandal, Sangchul Hwang

Keywords(s): Ecofriendly, Skin Safe Absorbent

Category(s): Materials, Life Science, Energy/Environment

Novel truncated miRNA-506-3p analogs for Neuroblastoma differentiation therapy

Description: Our research has developed a series of shortened miR-506-3p analogs designed to maintain strong differentiation-inducing activities comparable to the wildtype miR-506-3p. These analogs have been tested for their ability to induce neurite outgrowth and cell growth arrest in neuroblastoma cells, demonstrating significant potential for therapeutic...

Published: 11/11/2025 | Inventor(s): Liqin Du, Nakya Mesa-Diaz, Mitchell Smith

Keywords(s): Childhood Cancer, Differentiation Therapy, Differentiation-Inducing Agent, MicroRNA, miR-506-3p, Neuroblastoma, Shortened miRNA, Truncated Analog, Wildtype (WT)

Category(s): Life Science, Cancer

Modulating stress responses by a novel chromatin-associated guide RNA derived from tRNA

Description: This technology revolves around the discovery of CANG-RNA, a type of tRNA-derived RNA fragment, and its critical role in plant immunity. By interacting with the genome, CANG-RNA facilitates a rapid and extensive transcriptional reprogramming, enabling plants to mount a strong defense against pathogens such as Pseudomonas syringae pv. tomato....

Published: 11/11/2025 | Inventor(s): Hong-Gu Kang, Sung-Il Kim

Keywords(s): Bio-Active RNA, Immunization, Stress, Transcriptional Reprogramming

Category(s): Agriculture, Life Science

NETFIO-MS(Network-Based Functional Imaging Output for Evaluating Multiple Sclerosis)

Description: NETFIO-MS is an innovative medical image analysis tool designed for use with resting-state functional MRI (rsfMRI) to quantitatively assess functional network-based disease burden in MS patients. By focusing on the functional network properties related to neurodegeneration, NETFIO-MS offers a novel approach to the early and accurate diagnosis...

Published: 11/11/2025 | Inventor(s): Larry Price

Keywords(s): Atrophy-Based Functional Network, Expanded Disability, Network Degeneration Hypothesis

Category(s): Life Science, Software, Data/AI

Herbicide and Environmental Stress Resistant Plants and Seeds

Description: This technology encompasses the development and use of genetically modified plants or seeds that are resistant to specific herbicides and various environmental stresses. By incorporating mutated genes, such as pic30 or its homologs, these plants or seeds can withstand conditions such as drought, plant diseases, and both biotic and abiotic...

Published: 11/11/2025 | Inventor(s): Nihal Dharmasiri, Sunethra Dharmasiri, Praveen Kathare

Keywords(s):

Category(s): Agriculture, Life Science

Photoactivatable Cancer Prodrug Photoactivatable Ruthenium Compounds for Cancer Treatment

Description: This technology introduces a new class of photoactivatable compounds based on ruthenium for the treatment of cancer. Leveraging the principles of photodynamic therapy (PDT), these compounds are designed to be activated by light to target and disrupt cancer cells selectively, while sparing healthy tissues. This innovative approach aims...

Published: 11/18/2025 | Inventor(s): Alexander Kornienko, Tania Betancourt, Shuster Bonnet, Vincent van Rixel

Keywords(s): Cancer Treatment, Photoactivatable Ruthenium Compounds, Photodynamic Therapy Photodynamic Therapy

Category(s): Cancer, Chemistry, Life Science

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