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Novel truncated miRNA-506-3p analogs for Neuroblastoma differentiation therapy
Description: Our research has developed a series of shortened miR-506-3p analogs designed to maintain strong differentiation-inducing activities comparable to the wildtype miR-506-3p. These analogs have been tested for their ability to induce neurite outgrowth and cell growth arrest in neuroblastoma cells, demonstrating significant potential for therapeutic...
Published: 12/19/2024
|
Inventor(s):
Liqin Du
,
Nakya Mesa-Diaz
,
Mitchell Smith
Keywords(s):
Childhood Cancer
,
Differentiation Therapy
,
Differentiation-Inducing Agent
,
MicroRNA
,
miR-506-3p
,
Neuroblastoma
,
Shortened miRNA
,
Truncated Analog
,
Wildtype (WT)
Category(s):
Biotechnology
,
Genetic Engineering
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