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Novel truncated miRNA-506-3p analogs for Neuroblastoma differentiation therapy

Description: Our research has developed a series of shortened miR-506-3p analogs designed to maintain strong differentiation-inducing activities comparable to the wildtype miR-506-3p. These analogs have been tested for their ability to induce neurite outgrowth and cell growth arrest in neuroblastoma cells, demonstrating significant potential for therapeutic...

Published: 12/19/2024 | Inventor(s): Liqin Du, Nakya Mesa-Diaz, Mitchell Smith

Keywords(s): Childhood Cancer, Differentiation Therapy, Differentiation-Inducing Agent, MicroRNA, miR-506-3p, Neuroblastoma, Shortened miRNA, Truncated Analog, Wildtype (WT)

Category(s): Biotechnology, Genetic Engineering