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Sphaeropsidin derivatives to combat aggressive cancers

Description: This technology involves the synthesis of new compounds based on the sphaeropsidin A structure, aimed at improving its potency against drug-resistant cancers. Utilizing a cross-metathesis reaction, these compounds have shown significant growth inhibitory activity in various human cancer cell lines, including glioblastoma, non-small cell...

Published: 12/19/2024 | Inventor(s): Alexander Kornienko, Dino Berthold, Antonio Evidente, Sachin Wagh, Willem van Otterlo, Aude Ingels, Veronique Mathieu

Keywords(s): Apoptosis, Cancer, Drug Resistance, Natural Products, Sphaeropsidin

Category(s): Biotechnology, Pharmaceutical Research